Master Regulator

Mike Robinson's shorthand for the Endocannabinoid System - a bodywide control network that keeps every other system in balance by sensing stress, shifting set points, and restoring stability in real time. What it is: Receptors like CB1 and CB2, endocannabinoids like anandamide and 2-AG, and enzymes like FAAH and MAGL that make and break them down. What it does: Tunes neurotransmitters, calms inflammation, guides pain signaling, shapes mood and sleep, steadies appetite and metabolism, supports gut motility and immune tone, and fosters neuroplasticity. How it works: Endocannabinoids are made on demand, act locally, then get cleared quickly - a tight feedback loop that prevents overreaction and brings systems back to baseline. Where it lives: Brain and nerves, immune cells, gut, skin, bones, reproductive organs - nearly everywhere you look. Call it The Master Regulator because it coordinates the rest - nervous, immune, endocrine, and more - so the whole body can adapt, recover, and stay balanced.