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Pyrrolizidine Alkaloidosis Tee

Pyrrolizidine alkaloidosis is a disease caused by chronic poisoning from ingesting plants that contain pyrrolizidine alkaloids (PAs), a group of more than 30 phytotoxins produced by various plants as a natural defense mechanism. These toxins are metabolized in the liver into highly reactive pyrroles, which cause cytotoxic effects by cross-linking DNA and other cellular macromolecules, leading to irreversible damage in target tissues, primarily the liver. The condition typically results in hepatic failure and is characterized by a delayed onset of clinical signs, often appearing weeks or months after exposure, even after consumption of the toxic plants has ceased. Pyrrolizidine alkaloidosis is most commonly associated with plants from the genera Senecio, Crotalaria, Heliotropium, Amsinckia, Echium, Cynoglossum, and Trichodesma, which grow in temperate, tropical, or subtropical climates. Animals such as cattle, horses, pigs, and farmed deer are particularly susceptible, with young, growing animals being most vulnerable. The disease can occur through ingestion of fresh plants, hay, silage, or contaminated grain, as some toxic compounds survive drying processes. Clinically, the disease manifests as progressive liver damage, with signs including loss of condition, anorexia, dullness, diarrhea, ascites, jaundice, and hepatic encephalopathy such as head-pressing, aimless wandering, or aggressive behavior.

Mug Hoodie

The Urban Dictionary Tee

Soft, comfortable fabric
Printed on-demand just for you
True to size fit
Pre-shrunk (won't shrink in wash)
Tear-away label (no itchy tags)
Every order personally reviewed

Customer Reviews

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FUCK you urban dictionary.

Nah N. Aug 21
Review by Malachy G.

My brother loved the shirt and the dogs name is cum stain

Malachy G. Aug 6
✓ Verified Purchase

The small shirts for men looks like an extra small. Other than that I love the shirt.

Dian C. Aug 5
✓ Verified Purchase

AMAZING I GOT THE HILAARIOUS SHIRT AND LOVE IT MORE THAN ANYTHING!

scarlett Jul 31
Review by Kristen G.

I absolutely loveeeeeeee my shirt ! Fast shipping too !

Kristen G. Jul 22
✓ Verified Purchase

hehe mine said skibidi

alpha g. Jul 22
Review by Fred F.

Feels great love the shitt

Fred F. Jul 3
✓ Verified Purchase

Great shirt. Great service. Shopify doesn’t track the shipment accurately though. However, when I reached out to Urban Dictionary customer service, they were able to help me.

Smitha M. Jul 3
✓ Verified Purchase

Wore it to school.

Monica L. Jun 28

Love this shirt so much

Joey L. Jun 16
✓ Verified Purchase
Review by No M.

I love this t-shirt that says morbussy. It allows me to show off both my love for Morbius and the fact that I get no Morbussy.

No M. Jun 15

This shirt feels great, perfect fit too.

Tyler S. Jun 6
✓ Verified Purchase

Great looking t-shirt. Good quality. Printing looks good.

Jane B. Jun 3
✓ Verified Purchase

Cool I didn’t order anything I just have a lot of free time and not a lot of hobbies

Hi May 31

Fun and soft.

Donald G. May 21
✓ Verified Purchase

Good stuff! Although, I do have a sneaking suspicion that this is cursed. You see, whenever i dawn this top-teir, soft, stylish shirt - I proceed to pass out within 46 seconds. The mere act of making contact with the material insues the process of this countdown starting. If I do not quit contact, i will lose conciousness the exact moment the countown hits 0. And when I regain clarity, I find myself in a bathtub - never mine, but a bathtub nevertheless. In the bathtub, there is always various colours of hairdye. I then have to go back home, shirt stained with dye. Very fashionable though! 10/10

Ally B. May 20

Smooth transaction and nice product, shipping was quick!

M U. May 16
✓ Verified Purchase

good very good worth money!

me May 9

5 out of 5 I love when people start reading the definition. It's halourious

Ayoush smith May 7

10/10 yes much good 10/10 would buy again

Some dude May 1
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