Pyrrolizidine Alkaloidosis Tee
Pyrrolizidine alkaloidosis is a disease caused by chronic poisoning from ingesting plants that contain pyrrolizidine alkaloids (PAs), a group of more than 30 phytotoxins produced by various plants as a natural defense mechanism. These toxins are metabolized in the liver into highly reactive pyrroles, which cause cytotoxic effects by cross-linking DNA and other cellular macromolecules, leading to irreversible damage in target tissues, primarily the liver. The condition typically results in hepatic failure and is characterized by a delayed onset of clinical signs, often appearing weeks or months after exposure, even after consumption of the toxic plants has ceased. Pyrrolizidine alkaloidosis is most commonly associated with plants from the genera Senecio, Crotalaria, Heliotropium, Amsinckia, Echium, Cynoglossum, and Trichodesma, which grow in temperate, tropical, or subtropical climates. Animals such as cattle, horses, pigs, and farmed deer are particularly susceptible, with young, growing animals being most vulnerable. The disease can occur through ingestion of fresh plants, hay, silage, or contaminated grain, as some toxic compounds survive drying processes. Clinically, the disease manifests as progressive liver damage, with signs including loss of condition, anorexia, dullness, diarrhea, ascites, jaundice, and hepatic encephalopathy such as head-pressing, aimless wandering, or aggressive behavior.
The Urban Dictionary Tee
Customer Reviews
I absolutely loveeeeeeee my shirt ! Fast shipping too !
hehe mine said skibidi
Feels great love the shitt
Great shirt. Great service. Shopify doesn’t track the shipment accurately though. However, when I reached out to Urban Dictionary customer service, they were able to help me.
Wore it to school.
Love this shirt so much
I love this t-shirt that says morbussy. It allows me to show off both my love for Morbius and the fact that I get no Morbussy.
This shirt feels great, perfect fit too.
Great looking t-shirt. Good quality. Printing looks good.
Cool I didn’t order anything I just have a lot of free time and not a lot of hobbies
Fun and soft.
Good stuff! Although, I do have a sneaking suspicion that this is cursed. You see, whenever i dawn this top-teir, soft, stylish shirt - I proceed to pass out within 46 seconds. The mere act of making contact with the material insues the process of this countdown starting. If I do not quit contact, i will lose conciousness the exact moment the countown hits 0. And when I regain clarity, I find myself in a bathtub - never mine, but a bathtub nevertheless. In the bathtub, there is always various colours of hairdye. I then have to go back home, shirt stained with dye. Very fashionable though! 10/10
Smooth transaction and nice product, shipping was quick!
good very good worth money!
5 out of 5 I love when people start reading the definition. It's halourious
10/10 yes much good 10/10 would buy again
Fit is true to size, good quality material. Graphics applied well (not off-center or angled as with some products). Quick shipment.
gooderesting the gooderesting thing ever made
Got it for a friend! He loved it
Size was accurate, and printed text was as displayed online. Doesn't hurt that the material is pretty soft either.