Despite

preposition UK /dɪˈspaɪt/ US /dɪˈspaɪt/ B1 without taking any notice of or being influenced by; not prevented by: I still enjoyed the week despite the weather. Despite repeated assurances that the product is safe, many people have stopped buying it. + -ing verb He managed to eat a big lunch despite having eaten an enormous breakfast. despite yourself If you do something despite yourself, you do it although you do not want to or although you know you should not: He laughed despite himself. She took the money from her mother's purse, despite herself.