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LSFI: Let Shit Fuck Itself. Let things take care of themselves, especially if they are crappy things that one is not too [interested] in [taking care] of anyway. Alternatively, could also mean let those things [go to hell], i.e. NOT take care of themselves, 'just don't bother me about them because I couldn't care less about them'. Variants include LTSFI, which can stand for Let This Shit Fuck Itself, OR Let That Shit Fuck Itself. A more aggressive variant is LTSFM - Let That Shit Fuck Me. This slightly changes the connotation from things just going to hell, to things becoming an active problem in one's own life, screwing with one.
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