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Alcohol Flush Reaction A condition caused by the incomplete metabolism of alcohol with [accumulation] of acetaldehyde due to a missense [polymorphism] in acetaldehyde dehydrogenase—ALDH2—resulting in bright red skin due to capillary dilation of face, neck, shoulder, and sometimes the entire body after consuming alcohol. Those with ALDH2 deficiency have up to a 10-fold greater risk of oesophageal cancer, attributed to the [accumulation] of acetaldehyde
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