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Verb. A side effect of extreme over indulgence in [crystal meth] or [crack cocaine]. Tweekers typically perform OCD-like activities centered around finding small quantities of drugs that were inadvertently "misplaced". Tweekers may be seen on all fours, searching in gutters, obsessively looking under various objects and so on. In certain [circumstances], extreme tweeking resembles autism or catatonia.
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