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A rare fatal autosomal recessive neurodegenerative disorder that begins in childhood, it is caused by mutation of the CLN3 gene.

Early symptoms of the disorder usually appear around ages 4-10, with gradual onset of vision problems, or seizures. Early signs may be subtle [personality] and behavior changes, slow learning or regression, repetitive speech or echolalia, clumsiness, or stumbling. There may be slowing head growth in the infantile form, poor circulation in lower extremities (legs and feet), decreased body fat and muscle mass, curvature of the spine, [hyperventilation] and/or breath-holding spells, teeth grinding, and [constipation].

Over time, affected children suffer mental impairment, worsening seizures, and progressive loss of sight, speech and motor skills. [Eventually], children with Batten disease become blind, bedridden, and demented. Batten Disease is a life limiting disease, life expectancy varies depending on the type or variation.

It normally affects very young children of ages like 4-6, but has been known to affect older people as well, Kufs affects adults and symptoms normally start in the 30's.

The prognosis is about 5-7 years and there is currently no cure.

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