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Derives from the game "[Metal Gear Solid 2]" it means "Mission Failed". which is used as a [derogative] term to slander someone/ someones argument that they've put forward in a debate, it is both patronizing and shows that you're putting an end to the argument. Considered to be part of l33t sp33k. [Gaming slang]. Often used as the end of a sarcastic comment.
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