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Promethazine with Codeine Cough Syrup, manufactured by Alpharma Inc. Each 5 mL tablespoon contains 6.25 mg promethazine hydrochloride and 10 mg codeine phosphate. Codeine is an opiate, a natural substance found in the opium poppy. However, it is rare and thus most medicinal codeine is created via the methylation of codeine (the addition of CH2). In Houston, Texas, it s a very popular beverage; the syrup is traditionally mixed in with soda and jolly ranchers.
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