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A Tennessee Alka-Seltzer is when you stick an alka-seltzer into your mouth, then have oral sex with a [Southern girl](with out telling her, but of course). As her vagina gets wet, you slip in the alka-seltzer, stand back, and watch the 'fire works'...or, in this case, 'foam works'. The 'Tennesse' part is derived from [college kids] out of D.C. going into Virginia on a [Saturday night], and performing it on innocent country 'gurls'. Why did I not choose 'Virginia' to make it a 'Virginia Alka-Seltzer'? Because Tennessee sounds better. And if you don't like it, piss off!
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