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G_nome is the ghetto variation of the biological word genome, which is a human's DNA sequence. The word is used mainly in the [description] of phat women and fly men who don't have to try to keep it gangsta. The term essentially means that one has fly-ness encoded in their DNA. There has also been a human G_nome project in which Micheal Moore went and did a [documentary] on life in the ghetto, however he was shot and [hospitalized] shortly there after.
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