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The direct, deliberate redesign of metabolic networks within [organisms] to achieve desired outcomes. This is synthetic biology's core discipline: hacking a cell's chemical factories to produce pharmaceuticals, biofuels, or materials. It involves inserting, deleting, or tuning genes to re-route biochemical traffic, turning microbes into living micro-factories. It's programming with DNA to make biology produce what we want, treating [metabolism] as [the ultimate] programmable machinery.
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