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4x100 (สี่คูณร้อย) A colloquial Thai term for a psychoactive beverage made by mixing kratom tea (Migranyan speciosa leaf decoction) with sweetened soft drinks and most commonly diphenhydramine (Benadryl)–based antihistamine syrup or tablets. The name “4x100” comes from the idea of four ingredients combined in 100 millilitres of liquid. Although other additives (such as codeine cough syrup or tramadol) may sometimes be included, diphenhydramine is the primary and most typical additive due to its wide availability and strong sedative effects. The drink produces a combination of stimulant and sedative properties but carries significant health risks.
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