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Cannabinoid hyperemesis syndrome (CHS) is when you smoke weed every week to everyday for several years and end up vomiting a lot.

What causes cannabinoid hyperemesis syndrome?
Marijuana has very complex effects on the body. Experts are still trying to learn exactly how it causes CHS in some people.

[In the brain], marijuana often has the [opposite effect] of CHS. It helps prevent nausea and vomiting. The drug is also good at stopping such symptoms in people having chemotherapy.

But in the digestive tract, marijuana seems to have the [opposite effect]. It actually makes you more likely to have nausea and vomiting. With the first [use] of marijuana, the signals from the brain may be more important. That may lead to anti-nausea effects at first. But with repeated use of marijuana, certain receptors in the brain may stop responding to the drug in the same way. That may cause the repeated bouts of vomiting found in people with CHS.

Since CHS was discovered pretty recently, some doctors might not know about it. Also, CHS is often confused with cyclical vomiting.

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