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When someone is referred to as "Piss pilled", it means that they're generally bitter, resentful, and often angry/upset at/towards others for no reason, or an irrational reason. They are called "Piss pilled" as a take on the 1999 film The Matrix, in which there is an option for the protagonist to take the red or blue pill, each with a different consequence. In recent years, red and blue pills have garnered more attention and relevance in popular [Internet culture], as they have gained deeper meanings, and more pills have been made up. Too long didn't read, [taking the Piss] pill means that you have chosen to live a life of "pissful ignorance," or a life where you are always pissed off and [everything sucks] for you.
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