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Dentinogenesis imperfecta is a developmental disease of the teeth. It is also a rare condition. Teeth become discoloured (most commonly a blue-gray or yellow-brown colour) and translucent as a result of this condition. Teeth are also weaker than normal, making them more prone to breakage, wear, and loss. It also means no enamel or calcium are in the teeth. Both primary (baby) teeth and permanent teeth can be affected by dentinogenesis imperfecta. This disease can also cause speech problems or teeth that aren't properly aligned in the mouth. Dentinogenesis imperfecta is inherited in an autosomal dominant way and is caused by mutations in the DSPP gene.
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