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TNBC refers to any breast cancer that does not express the genes for the 3 most common breast cancers, namely, Estero gen receptor (ER), progesterone receptor (PR) and HER2/neu. TNBC is more difficult to treat because most hormone therapies target one of the 3 receptors. Triple-negative here hs a medical meaning. Triple-negative here does not mean an added negative to a double-negative.
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