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preposition UK /dɪˈspaɪt/ US /dɪˈspaɪt/ B1 without taking any notice of or being influenced by; not prevented by: I still enjoyed the week despite the weather. Despite repeated assurances that [the product] is safe, many people have stopped buying it. + -ing verb He managed to eat a big lunch despite having eaten an enormous breakfast. despite yourself If you [do something] despite yourself, you do it although you [do not want] to or although you know you should not: He laughed despite himself. She took the money from her mother's purse, despite herself.
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