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The most rural Interstate (except maybe I-8). Between San Antonio and Los Angeles, I-10 is either in a large town or in absolute nothingness. It has an intersection with I-20 in the middle of nowhere in Texas, 130 miles from El Paso and 450 miles from San Antonio. Of somewhat interest is "The Thing". I myself do not know what that is but it is located near Texas Canyon, Arizona, on I-10. I-10 passes through these major cities: Los Angeles, Phoenix, Tucson, El Paso (even though nobody would put it on this list), San Antonio, Houston, New Orleans, and Jacksonville.
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