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Refering to someone with Downs Syndrome - so really should be "downsie" It is a genetic condition that is increasingly common the older the mother of a child is when she falls pregnant. Downs Sydrome is caused by non disjunction of the 21st chromosome (humans have 23 pairs of chromosomes - each parent supplies 23 chromosomes to the child getting a total of 46) which means chromosome 21 in the mother has not split like it should when making sex cells (gametes) and the child ends up with 3 copies of chromosome 21 compared to the usual 2. Some characteristics of downs syndrome include:  Poor muscle tone Slanting eyes with folds of skin at the inner corners (called epicanthal folds) Hyperflexibility (excessive ability to extend the joints) Short, broad hands with a single crease across the palm on one or both hands Broad feet with short toes Flat bridge of the nose Short, low-set ears Short neck Small head Small oral cavity Short, high-pitched cries in infancy  Sufferers of Downs Syndrome are ussually smaller than their normal peers and their physical and intellectual development is ussually slower.

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