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Wise Mule Syndrome: A condition in which one cannot stop being a smart ass, regardless of race, culture, situation, alcoholic content, or media. While the contemporary social view is that clinical sufferers of this condition are choosing to be a smart ass, it is in fact, medically impossible for them not to be without the proper medication. If you encounter someone who has been diagnosed with WMS the proper response is to either back away slowly, or laugh at everything they say as the are inwardly sensitive and self-conscious. And awesome.
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