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(1) Any doomsday catalyst; any precipitator which brings about cataclysmic, apocalyptic change -- yes, Virginia, THE END of the world, Armageddon, "that's all she wrote", APOCALYPTIC #FAIL! (2) The Unholy Grail of overzealous scientists who in the thoughtless pursuit of "pure science" unwittingly create a doomsday device. (3) Specifically, the fictional doomsday catalyst envisioned by Kurt Vonnegut in his novel "Cat's Cradle." Ironically, the inventor of Vonnegut's "ice-nine" never intended his creation to be used as a doomsday device; this shortsighted scientist only foresaw "ice-nine" being used for the ploddingly pedestrian purpose of making it possible for combat Marines to march over mud in much the same manner that Jesus is said to have come striding across the tempest-tossed waves of the Sea of Galilee (Matthew 14:24).
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