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A form of YouTube spam where YouTube users, typically idiotic women with oversized breasts, decide to upload a video entitled "RE: Videoname" and post it as a video reply. As a result, they manage to fill the "Related Videos" section of YouTube with a plethora of breasts, as opposed to actual content that's actually related to the current video. Most YouTube users view Reply Girls as a nuisance. There are some people who enjoy the Reply Girls, but all they look at are the thumbnails with their exposed cleavage, leave a stupid-ass comment, and then leave the video.
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