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Intoxicated, inebriated, drunk, under the influence of alcohol. It is sometimes used to denote ire or anger, but when it is it is usually always said 'pissed off'. According to some sources the origins of 'pissed' derive from the practices of pagan northern european peoples imbibing the urine of others (primarily shamen) who had ingested the Amanita Muscaria mushroom to obtain its active compounds.
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