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The sudden urge one gets to leave (or have your "tweener" leave) almost immediately after having had sex with your "tweener", regardless or sexual gratification. (Tweener (adj): People who are sexually intimate with when they are both between relationships - similar to friends with benefits, but with the expectation that while the friendship will continue, the benefits are put aside when one of the people involved gets involved in a romantic relationship.) This is not to be confused with one-night stand remorse or anxiety, since tweeners are not usually just one night stands.
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