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1. Getting prescribed two medicines at the same time(two anti-depressants or anti-psychotic medications.) Happens to patients in mental hospitals who have very long stay periods. This is border line illegal and frowned upon. Often for those who have to deal with the extremely high dosages of these medications it causes a plethora of problems: lethargy, emotionless state, digestion problems, memory problems, etc. 2. The act of taking ecstacy with mushrooms. Could also mean any combination of hard drugs taken together or just using drugs. 3. Sexual act where one has sex both anally and vaginally. Also means sex with two people, hooking up with multiple girls behind their back, etc.
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