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1. a female known for having an unusually high tolerance for heroin or other opiates 2. a female who is known to act very courageously while [under the influence] of heroin or other opiates 3. a person who types the word "heroine" when trying to refer to the drug derived from the poppy plant (heroin) example 1: john: i cant believe how high your tolerance to opiates is.. jane: ya i guess im a real heroin heroine example 2: ([text message]) "man im so high off that heroine i just smoked" (reply) "learn [how to spell] you stupid heroin heroine"
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