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This phrase is a greeting of endearment between Latino gangster youth culture. Ese (masculine) and esa (feminine) are comparable to homeboy or homegirl. The phrase if said by a non-Hispanic is [extremely] [offensive]. It is comparable to the phrase, "What up, My n*gger?" in the Latino community. Also, the use of homes is [derogatory] because it is urban Latino gangster ideology.
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