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Noun, verb The resulting product, or the action of mixing together two illegal drugs to be consumed at the same time; e.g. cocaine and mdma, ketamine and cocaine, mdma and ketamine. Usually snorted. And preceeded by chanting 'mix and blend' in a London/ West Indian accent in the faces of people who are not invited to join in, or probably don't want to. Doing a mix and blend usually results in loss of memory and confused emotions the following day, but these symptoms can be relieved by just not going to bed.
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