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Van Buren is the red-light district of Phoenix, Arizona. When people talk about "Van Buren" in this sense, they are usually referring to the stretch of Van Buren St. east of Central Ave. before the road becomes Mill Ave. at Papago Park. The nature of the area is made more obvious by the overabundance of cheap motels. Most residents of the Valley of the Sun as well as many other Arizona residents know of the reputation of the street. It's also commonly used in jokes.
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