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A philosophical framework holding that evidence is shaped by multiple, irreducible contexts—scientific, social, cultural, historical, practical—that interact to constitute what counts as evidence. Evidence multicontextualism insists that no single context exhausts the meaning of evidence and that understanding evidence requires mapping how contexts interrelate. A clinical trial's evidence is shaped by the context of trial design, the context of funding, the context of participant selection, the context of statistical interpretation, and the context of clinical practice—all of which interact. This framework demands that we resist reductionist approaches to evidence and embrace the complexity of how evidence is produced, interpreted, and applied across interacting contexts.
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