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The more sophisticated successor's struggle: trying to ground science and meaning in logic and empirical data while wrestling with the realization that observation is theory-laden, and no final, pure "protocol sentence" exists. The hard problem is that the boundary between analytic (logic/math) and synthetic (empirical) statements, which the whole system relied on, turned out to be blurry. Quine's "web of belief" showed you can't test a single statement in isolation—you can always save a cherished hypothesis by adjusting other parts of the network.
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