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Guh has many meanings. According to the r/Guh1 subreddit, the subreddit dedicated to the use of Guh, it is whatever you'd like it to be. That being said, here's the actual meaning: When you can't conjure up a reply, basically what people use "Yeah" "Yea" "Lol" and "Lmao" for. Can also be used for anything weird.
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