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Generally, any antidepressant or antianxiety medication, especially one prescribed and taken every day. "Crazy pills" is a light-hearted, self-deprecating way of talking about these medications with close friends, trusted acquaintances, etc., without bringing the associated (and unnecessary) social stigma along for the ride. If used in conversation with a person you do not know, the intended meaning may be lost. Common examples: Zoloft (sertraline), Lexapro, Wellbutrin.
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