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Anhedonia is closely linked to depression, but you don't have to be depressed or feel sad to have it. It also affects people with other mental illnesses, like schizophrenia and bipolar disorder. And it can show up in people with seemingly unrelated health concerns like Parkinson's disease, diabetes, coronary artery disease, and substance abuse issues. Scientists think anhedonia may be tied to changes in brain activity. You might have a problem with the way your brain produces or responds to dopamine, a "feel-good" mood chemical. Some early research (on rats) suggests that the dopamine neurons in an area of the brain called the prefrontal cortex might be overactive in people with anhedonia. This somehow interferes with pathways that control how we seek out rewards and experience them
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