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Commonly used in sports, to "take it to the house" means to score a point in a big play. The term is almost always used in the context of American football, usually after a player gets a large breakthrough play and takes it all the way to the endzone after a long run. This term is also applicable in American football when a player catches an interception and runs it all the way for a touchdown (coined as pick six) or when a player returns a field goal kick that was either short or blocked (coined as kick six after the 2013 Auburn-Alabama game).
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