Cross-dressing transexual. As seen in "Silence of the Lambs" film and also mocked in "American Pie 3: The Wedding". A Buffalo Bill is a guy who wants to have a sex change and looks like a girl.
"It put the dress in the drawers" or "It rubs the lotion on the skin unless it wants the hose again".
By George
the awful sensation of fire from down below is caused when any food you have consumed contains excessive amounts of fast moving "picante" sludge to explode from your ass. some side effects include the fact that if powerful enough "picante" turds in liquid form fly from between tiolet and seat and hit bathroom walls or anything that is unfourtinute to be in the way for that matter. taco bell anyone?
call me "buffalo bill" dude, the spirit of the old west just ran through my bowels
By ghetto kung fu champion
noun -A skinny guy that digs great big fat chicks.
"Hey, check Jimmy out with that fat chick." "Yeah he's Buffalo Bill, says it guarantees that he'll get laid."
By The Afterworld Cafe
(v.) The act of taming a wild stallion. Note: Often used to described the taming of a man or beast who displays a spirit very similar to that of a stallion.
..so I grabbed my end of the lasso as firm as I could while I got on that mare's back, and then I buffalo bill'd that horsey 'til only one of us was left standing.
By arf79
A man named jerome who stares at you from the countertop while you do anythng in the kitchen
dammit Jerome is such a buffalo bill, i hate how he stares at me
By leeskot